Maresin compound treatments for multiple indications

The next frontier of natural pain relief

Maresin compounds are critical components of the inflammation resolution machinery, meaning their benefits are not limited to a single disease. Their therapeutic potential extends to many indications involving unresolved inflammation and chronic pain. Our mission is to expand and enhance treatment options for patients suffering from conditions, including:

Systemic lupus erythematosus (SLE)

As part of their inflammation resolution machinery, maresin compounds promote the clearance of dead cells – a process known as efferocytosis. This suggests that maresin compounds could potentially offer benefits for diseases characterized by a failure to remove dead cells, such as autoimmune disease like systemic lupus erythematosus (SLE).1 To explore this further, we are currently developing a MaR1 analog as an injectable treatment for SLE.

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Inflammatory skin conditions met

Evidence suggests that MaR1 can control inflammation and promote tissue repair in skin conditions such as vitiligo, psoriasis and atopic dermatitis. Recognizing this promising therapeutic potential, we are leveraging our MaR102 topical formulation to conduct an accelerated development program for inflammatory skin conditions, partially based on preclinical data generated during the vulvodynia trial.

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Oncology

Given that inflammation is a hallmark of cancer, we are curious about whether maresin compounds could become a novel solution to support cancer treatment through inflammation resolution. That’s why we are preparing to investigate this exciting possibility in the future.

At SPM Therapeutics, we are not just following the science – we're driving it forward. Pushing the boundaries of what is possible in high-performing pain relief and actively redefining standards across the therapeutics landscape.

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Leaders in targeting inflammation and pain at the source